Drug Information

Drug General Information
Drug ID
D09FTZ
Former ID
DNC004008
Drug Name
(4-Phenylethynyl-cyclohex-3-enyl)-dipropyl-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525701]
Structure
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2D MOL

3D MOL
Formula
C20H27N
Canonical SMILES
CCCN(CCC)C1CCC(=CC1)C#CC2=CC=CC=C2
InChI
1S/C20H27N/c1-3-16-21(17-4-2)20-14-12-19(13-15-20)11-10-18-8-6-5-7-9-18/h5-9,12,20H,3-4,13-17H2,1-2H3
InChIKey
QQFDMLZEFWKHHH-UHFFFAOYSA-N
PubChem Compound ID
10564794
Target and Pathway
Target(s) D(3) dopamine receptor Target Info Inhibitor [525701]
D(4) dopamine receptor Target Info Inhibitor [525701]
KEGG Pathway Neuroactive ligand-receptor interaction
Dopaminergic synapsehsa04080:Neuroactive ligand-receptor interaction
Dopaminergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling eventsR-HSA-390651:Dopamine receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
GPCRs, OtherWP666:Hypothetical Network for Drug Addiction
Genes and (Common) Pathways Underlying Drug Addiction
GPCRs, Other
References
Ref 525701J Med Chem. 2000 Feb 24;43(4):756-62.Conjugated enynes as nonaromatic catechol bioisosteres: synthesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the D(3) subtype.
Ref 525701J Med Chem. 2000 Feb 24;43(4):756-62.Conjugated enynes as nonaromatic catechol bioisosteres: synthesis, binding experiments, and computational studies of novel dopamine receptor agonists recognizing preferentially the D(3) subtype.

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