Drug Information

Drug General Information
Drug ID
D09HOW
Former ID
DIB016165
Drug Name
S-364735
Synonyms
GSK-364735; HIV integrase inhibitors (2), Shionogi/GlaxoSmithKline
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Phase 2 [521915]
Company
Shionogi
Structure
Download
2D MOL

3D MOL
Canonical SMILES
c1(ccc(cc1)Cc1cc2c(nc1)c(c(c(=O)n2C)C(=O)NCCO)O)F
Target and Pathway
Target(s) HIV integrase Target Info Inhibitor [529234]
References
Ref 521915ClinicalTrials.gov (NCT00398125) Monotherapy Versus Placebo Over 10 Days in Integrase Naive HIV-1 Infected Adults. U.S. National Institutes of Health.
Ref 529234The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral. Antimicrob Agents Chemother. 2008 Mar;52(3):901-8. Epub 2007 Dec 26.

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