TTD | Drug: D09ICL

Drug General Information
Drug ID	D09ICL
Former ID	DIB020658
Drug Name	PD-118057
Synonyms	PD118057; PD 118057
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542655]
Structure		Download 2D MOL
Formula	C21H17Cl2NO2
InChI	InChI=1S/C21H17Cl2NO2/c22-18-12-9-15(13-19(18)23)6-5-14-7-10-16(11-8-14)24-20-4-2-1-3-17(20)21(25)26/h1-4,7-13,24H,5-6H2,(H,25,26)
InChIKey	ZCQOSCDABPVAFB-UHFFFAOYSA-N
PubChem Compound ID	9864959
PubChem Substance ID	14829677, 24157076, 24724580, 29217628, 45287227, 50111713, 50111714, 57373594, 79644140, 103608866, 129883541, 134224798, 137235486, 138164541, 143035268, 162248072, 163125609, 204362253, 223366011, 223854232, 232193730, 241376140, 249617699, 252156821
Target and Pathway
Target(s)	Potassium voltage-gated channel subfamily H member 2	Target Info	Activator	[527605]
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	Voltage gated Potassium channels
WikiPathways	SIDS Susceptibility Pathways
	Hematopoietic Stem Cell Differentiation
	Potassium Channels
References
Ref 542655	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7676).
Ref 527605	Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity. Mol Pharmacol. 2005 Sep;68(3):876-84. Epub 2005 Jun 23.

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Drug Information