Drug General Information
Drug ID	D09JYF
Former ID	DIB011945
Drug Name	Epocarbazolin-A
Synonyms	Epocarbazolin-B
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Terminated	[534037]
Company	Bristol-Myers Squibb Co
Structure		Download 2D MOL 3D MOL
Formula	C22H27NO4
Canonical SMILES	C1(OC1(CCC(C)C)C)c1c2[nH]c3c(c2cc(c1C)O)c(ccc3O)CO
CAS Number	CAS 146935-39-9
PubChem Compound ID	192365
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Inhibitor	[534037]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 534037	Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. J Antibiot (Tokyo). 1993 Jan;46(1):25-33.
Ref 534037	Epocarbazolins A and B, novel 5-lipoxygenase inhibitors. Taxonomy, fermentation, isolation, structures and biological activities. J Antibiot (Tokyo). 1993 Jan;46(1):25-33.

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