Drug General Information
Drug ID	D09LQP
Former ID	DIB004096
Drug Name	RG-14893
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Terminated	[544957]
Company	Rhone-Poulenc SA
Structure		Download 2D MOL 3D MOL
Formula	C29H27NO4
Canonical SMILES	c1(c2c(cc(C(=O)O)c1)c(OCc1ccccc1)ccc2)CC(=O)N(CCc1ccccc<br />1)C
CAS Number	CAS 141835-49-6
PubChem Compound ID	132379
Target and Pathway
Target(s)	Leukotriene B4 receptor 1	Target Info	Modulator	[534207]
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	IL4 Signaling Pathway
Reactome	Leukotriene receptors
	G alpha (q) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Spinal Cord Injury
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 544957	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001715)
Ref 534207	Structure-activity relationships study of two series of leukotriene B4 antagonists: novel indolyl and naphthyl compounds substituted with a 2-[methyl(2-phenethyl)amino]-2-oxoethyl side chain. J Med Chem. 1996 Sep 13;39(19):3756-68.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.