Drug General Information
Drug ID	D09NNI
Former ID	DNC011819
Drug Name	3-Methoxy-9H-beta-carboline
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533363]
Structure		Download 2D MOL 3D MOL
Formula	C12H10N2O
Canonical SMILES	COC1=NC=C2C(=C1)C3=CC=CC=C3N2
InChI	1S/C12H10N2O/c1-15-12-6-9-8-4-2-3-5-10(8)14-11(9)7-13-12/h2-7,14H,1H3
InChIKey	UFGGNIMGPVLCJZ-UHFFFAOYSA-N
PubChem Compound ID	363113
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[533363]
	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[533363]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.

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