Drug General Information
Drug ID	D09PTR
Drug Name	FR-900452
Synonyms	101706-33-6; FR-900452
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1559751]
Structure		Download 2D MOL 3D MOL
Formula	C22H25N3O3S
PubChem Compound ID	3035856
Target and Pathway
Target(s)	Platelet-activating factor receptor	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Staphylococcus aureus infection
NetPath Pathway	IL5 Signaling Pathway
	Leptin Signaling Pathway
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (q) signalling events
	Interferon gamma signaling
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Interferon gamma signaling
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 1559751	FR-900452, a specific antagonist of platelet activating factor (PAF) produced by Streptomyces phaeofaciens.I.Taxonomy, fermentation, isolation, and physico-chemical and biological characteristics.J Antibiot (Tokyo).

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