Drug Information

Drug General Information
Drug ID
D09QKI
Former ID
DIB012821
Drug Name
PPL-100
Synonyms
HIV protease inhibitors, Ambrilia; HIV protease inhibitors, Pharmacor; HIV protease inhibitors, Procyon; HIV protease inhibitors, TaiMed; MK-8122; P-1946; PL-100; PL-337; HIV protease inhibitors, Merck & Co
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Preclinical [547190]
Company
Pharmacor Inc
Structure
Download
2D MOL

3D MOL
Formula
C33H45N4O9PS
Canonical SMILES
c1c(ccc(c1)S(=O)(=O)N([C@H](COP(=O)(O)O)CCCCNC(=O)[C@@H<br />](NC(=O)OC)C(c1ccccc1)c1ccccc1)CC(C)C)N
PubChem Compound ID
11563875
Target and Pathway
Target(s) HIV protease Target Info Inhibitor [528026]
References
Ref 547190Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013779)
Ref 528026Antiviral activity and cross-resistance profile of P-1946, a novel human immunodeficiency virus type 1 protease inhibitor. Antiviral Res. 2006 Jun;70(2):17-20. Epub 2006 Jan 20.

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