Drug Information

Drug General Information
Drug ID
D09QUQ
Former ID
DAP001233
Drug Name
Levobupivacaine
Synonyms
Novabupi; Chirocaine (TN); Levobupivacaine (INN); Levobupivacaine [INN:BAN]; Novabupi (TN); L(-)-Bupivacaine; L-(-)-bupivacaine; L-(-)-1-Butyl-2',6'-pipecoloxylidide; (-)-bupivacaine; (2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; (S)-1-Butyl-2',6'-pipecoloxylidide; (S)-bupivacaine
Drug Type
Small molecular drug
Indication Anesthesia [ICD9: 338; ICD10:R20.0] Approved [538559], [542226]
Therapeutic Class
Anesthetics
Company
AstraZeneca
Structure
Download
2D MOL

3D MOL
Formula
C18H28N2O
InChI
InChI=1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)/t16-/m0/s1
InChIKey
LEBVLXFERQHONN-INIZCTEOSA-N
CAS Number
CAS 27262-47-1
PubChem Compound ID
92253
PubChem Substance ID
10089, 10225294, 11112642, 14775644, 14800000, 29215441, 44423110, 46505295, 50010834, 50070564, 50071325, 57335205, 80394341, 93166629, 96024806, 104222110, 104406939, 123092444, 126592946, 126669543, 126669544, 128475942, 131308447, 134338472, 135048182, 136357477, 137248692, 160964338, 162174730, 163366975, 175271332, 178103786, 179150260, 185974045, 187072685, 198980870, 218903197, 223535869, 223666603, 223666604, 223850360, 226420984, 251916836, 251918075, 252451169
SuperDrug ATC ID
N01BB10
SuperDrug CAS ID
cas=027262471
Target and Pathway
Target(s) Sodium channel Target Info Blocker [535077]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 538559FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020997.
Ref 542226(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7211).
Ref 535077Block of neuronal tetrodotoxin-resistant Na+ currents by stereoisomers of piperidine local anesthetics. Anesth Analg. 2000 Dec;91(6):1499-505.

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