Drug Information

Drug General Information
Drug ID
D09ROV
Former ID
DNC001038
Drug Name
Nortropinyl-arylsulfonylurea 3
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535851]
Structure
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2D MOL

3D MOL
Formula
C22H24ClN3O5S
Canonical SMILES
C1CC2CC(CC1N2NC(=O)NS(=O)(=O)C3=CC=C(C=C3)Cl)OC(=O)CC4=<br />CC=CC=C4
InChI
1S/C22H24ClN3O5S/c23-16-6-10-20(11-7-16)32(29,30)25-22(28)24-26-17-8-9-18(26)14-19(13-17)31-21(27)12-15-4-2-1-3-5-15/h1-7,10-11,17-19H,8-9,12-14H2,(H2,24,25,28)/t17-,18+,19?
InChIKey
JLAXGKPNMOZKMF-DFNIBXOVSA-N
PubChem Compound ID
10367758
PubChem Substance ID
15381277, 34000772, 79608159, 103350493, 104024958, 134340296
Target and Pathway
Target(s) Steryl-sulfatase Target Info Inhibitor [535851]
KEGG Pathway Steroid hormone biosynthesis
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Glycosphingolipid metabolism
WikiPathways Estrogen metabolism
Vitamin D Receptor Pathway
Sphingolipid metabolism
References
Ref 535851Nortropinyl-arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3673-7.
Ref 535851Nortropinyl-arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3673-7.

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