Drug Information

Drug General Information
Drug ID
D09WNK
Former ID
DAP001478
Drug Name
Fenfluramine
Synonyms
Acino; Adifax; Adipomin; Dexafenfluramine; Dexfenfluramina; Dexfenfluramine; Dexfenfluraminum; Dextrofenfluramine; Fenfluramina; Fenfluraminum; Isomeride; Obedrex; Pesos; Ponderex; Rotondin; Dexfenfluramina [Spanish]; Dexfenfluraminum [Latin]; Fenfluramina [DCIT]; Fenfluramine hydrochloride; Levofenfluramine [INN]; Ponderax PA; S 768; D-Fenfluramine; Dexfenfluramine [INN:BAN]; Fenfluramine (INN); Fenfluramine [INN:BAN]; Fenfluraminum [INN-Latin]; Ponderax (TN); Fenfluramine, (+-)-Isomer; N-Ethyl-alpha-methyl-3-trifluoromethylphenethylamine; D-N-Ethyl-alpha-methyl-m-trifluoromethylphenethylamine; N-Ethyl-alpha-methyl-3-(trifluoromethyl)benzeneethanamine; N-Ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine; N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine; Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-(9CI); Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-, (S)-(9CI);Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-, (+-)-(9CI); (+)-Fenfluramine; (+-)-Fenfluramine; (+/-)-Fenfluramine hydrochloride; (S)-Fenfluramine; 1-(m-trifluoromethyl-phenyl)-2-ethylaminopropane; 1-(meta-Trifluoromethyl-phenyl)-2 ethylaminopropane; 2-Ethylamino-1-(3-trifluoromethylphenyl)propane; 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Withdrawn from market [467853], [537068]
Structure
Download
2D MOL

3D MOL
Formula
C12H16F3N
InChI
InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3
InChIKey
DBGIVFWFUFKIQN-UHFFFAOYSA-N
CAS Number
CAS 458-24-2
PubChem Compound ID
3337
PubChem Substance ID
9209, 3249386, 5309215, 8152120, 10321808, 10523352, 11336155, 11361394, 11462366, 15172399, 29215428, 29222472, 46506096, 48259332, 48416003, 50004501, 50004502, 50004503, 50109858, 50109859, 57321735, 77105779, 85209461, 92714658, 92729648, 96024640, 99313648, 103293190, 104303215, 117434287, 117434288, 124360345, 124892216, 125823537, 126629461, 126688542, 127709649, 134338464, 134338672, 134973127, 135120528, 136350838, 137100754, 139029041, 144205250, 148028517, 160963919, 164788577, 178101333, 179148561
SuperDrug ATC ID
A08AA02
SuperDrug CAS ID
cas=000458242
Target and Pathway
Target(s) 5-hydroxytryptamine receptor Target Info Antagonist [536103]
References
Ref 467853(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4613).
Ref 537068Obesity: pathophysiology and clinical management. Curr Med Chem. 2009;16(4):506-21.
Ref 536103Pharmacotherapy for obesity. Drugs. 2005;65(10):1391-418.

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