Drug Information

Drug General Information
Drug ID
D0A1HH
Former ID
DNC006820
Drug Name
1-(1-phenyl-2-o-tolylethyl)piperazine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528224]
Structure
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2D MOL

3D MOL
Formula
C19H24N2
Canonical SMILES
CC1=CC=CC=C1CC(C2=CC=CC=C2)N3CCNCC3
InChI
1S/C19H24N2/c1-16-7-5-6-10-18(16)15-19(17-8-3-2-4-9-17)21-13-11-20-12-14-21/h2-10,19-20H,11-15H2,1H3
InChIKey
XPYLNZBNFQMTKZ-UHFFFAOYSA-N
PubChem Compound ID
44414708
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [528224]
Sodium-dependent noradrenaline transporter Target Info Inhibitor [528224]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter ActivityWP727:Monoamine Transport
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 528224Bioorg Med Chem Lett. 2006 Aug 15;16(16):4345-8. Epub 2006 Jun 5.N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.
Ref 528224Bioorg Med Chem Lett. 2006 Aug 15;16(16):4345-8. Epub 2006 Jun 5.N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.

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