Drug General Information
Drug ID
D0A6RU
Former ID
DNC013438
Drug Name
7-chloro-1H-indazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528763]
Structure
Download
2D MOL

3D MOL

Formula
C7H5ClN2
Canonical SMILES
C1=CC2=C(C(=C1)Cl)NN=C2
InChI
1S/C7H5ClN2/c8-6-3-1-2-5-4-9-10-7(5)6/h1-4H,(H,9,10)
InChIKey
WIYOYUQVNPTVQG-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Nitric-oxide synthase, brain Target Info Inhibitor [528763]
BioCyc Pathway Citrulline-nitric oxide cycle
KEGG Pathway Arginine and proline metabolism
Metabolic pathways
Calcium signaling pathway
Phagosome
Circadian entrainment
Long-term depression
Salivary secretion
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
NetPath Pathway EGFR1 Signaling Pathway
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Arginine and Proline Metabolism
Reactome ROS production in response to bacteria
Nitric oxide stimulates guanylate cyclase
WikiPathways Monoamine Transport
Myometrial Relaxation and Contraction Pathways
Amyotrophic lateral sclerosis (ALS)
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
Spinal Cord Injury
Alzheimers Disease
Effects of Nitric Oxide
Serotonin Transporter Activity
References
Ref 528763Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. Epub 2007 Mar 14.4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase.
Ref 528763Bioorg Med Chem Lett. 2007 Jun 1;17(11):3177-80. Epub 2007 Mar 14.4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase.

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