Drug General Information
Drug ID	D0AK9V
Drug Name	VRX-03011
Synonyms	5-HT4 agonist (cognition/neuroprotectant), EPIX; VRX-03011
Indication	Unspecified		Investigative	[1559996]
Structure		Download 2D MOL
Target and Pathway
Target(s)	5-hydroxytryptamine 4 receptor	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	5HT4 type receptor mediated signaling pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 1559996	VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux.Neuropharmacology.2007 Sep;53(4):563-73.

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