Drug Information

Drug General Information
Drug ID
D0AO9S
Former ID
DAP000799
Drug Name
Enflurane
Synonyms
Alyrane; Efrane; Enflurano; Enfluranum; Enfran; Enlirane; Ethrane; Etran; Methylflurether; Abbott Brand of Enflurane; AstraZeneca Brand of Enflurane; Baxter Anaesthesia Brand of Enflurane; Pisa Brand of Enflurane; Zeneca Brand of Enflurane; Anesthetic 347; C 347; OHIO 347; Anesthetic Compound No. 347; Enflurane [Anaesthetics,volatile]; Enflurano [INN-Spanish]; Enfluranum [INN-Latin]; Ethrane (TN); Enflurane (JP15/USP/INN); Enflurane [USAN:BAN:INN:JAN]; Ether, 2-chloro-1,1,2-trifluoroethyl difluoromethyl; (+-)-2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
Drug Type
Small molecular drug
Indication Anesthesia [ICD9: 338; ICD10:R20.0] Approved [538275], [542185]
Therapeutic Class
Anesthetics
Structure
Download
2D MOL

3D MOL
Formula
C3H2ClF5O
InChI
InChI=1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H
InChIKey
JPGQOUSTVILISH-UHFFFAOYSA-N
CAS Number
CAS 13838-16-9
PubChem Compound ID
3226
PubChem Substance ID
9719, 412027, 3159891, 3723211, 5141500, 7847609, 7979165, 8145857, 8152049, 10507438, 15017403, 29222367, 46505314, 48413717, 49857358, 50112675, 51014447, 57321670, 81065519, 103385283, 104302894, 118838433, 124893307, 125363753, 126651887, 128307820, 131499045, 134338084, 134989789, 135590731, 136986714, 137008459, 139078461, 143459061, 143799467, 144205979, 144207364, 151992462, 160841876, 160963576, 162129908, 162303127, 162789551, 163406911, 164809625, 165235538, 176321093, 178103750, 179116667, 184554139
ChEBI ID
ChEBI:4792
SuperDrug ATC ID
N01AB04
SuperDrug CAS ID
cas=013838169
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Suppressor [535053]
References
Ref 538275FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074396.
Ref 542185(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7175).
Ref 535053Enflurane directly depresses glutamate AMPA and NMDA currents in mouse spinal cord motor neurons independent of actions on GABAA or glycine receptors. Anesthesiology. 2000 Oct;93(4):1075-84.

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