Drug Information

Drug General Information
Drug ID
D0B3UJ
Former ID
DIB004838
Drug Name
Paliperidone
Synonyms
Xeplion; Invega Sustenna; Paliperidone palmitate; JNS-010; Paliperidone (depot injection, NanoCrystal); Paliperidone (injectable, NanoCrystal), Elan; Paliperidone (depot injection, NanoCrystal), Johnson & Johnson
Drug Type
Small molecular drug
Indication Schizophrenia [ICD9: 295; ICD10:F20] Approved [524773], [542276], [551871]
Company
Johnson & Johnson
Structure
Download
2D MOL

3D MOL
Formula
C23H27FN4O3
InChI
InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3
InChIKey
PMXMIIMHBWHSKN-UHFFFAOYSA-N
CAS Number
CAS 199739-10-1
PubChem Compound ID
115237
PubChem Substance ID
10236700, 14905143, 22395187, 29296762, 46506296, 47207025, 50035150, 51002222, 57339070, 85229944, 85246150, 90341688, 92719038, 92729808, 103604037, 103910909, 104105311, 104397925, 118046559, 121361150, 125307525, 125341102, 126584511, 126621140, 126649064, 126650388, 126667060, 128939139, 131465791, 131549340, 134338126, 135072932, 136367845, 137166111, 142528484, 144116334, 152258953, 152344196, 160647798, 160810375, 160964597, 162185890, 163088563, 163371020, 163564516, 163981461, 164175255, 164785605, 170501956, 171063034
Target and Pathway
Target(s) 5-hydroxytryptamine receptor Target Info Antagonist [551871]
References
Ref 524773ClinicalTrials.gov (NCT02146547) European Long-acting Antipsychotics in Schizophrenia Trial. U.S. National Institutes of Health.
Ref 542276(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7258).
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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