Drug General Information
Drug ID	D0B4LD
Former ID	DNC007748
Drug Name	(2-biphenyl-3-yl-ethyl)-dimethyl-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528780]
Structure		Download 2D MOL 3D MOL
Formula	C16H19N
Canonical SMILES	CN(C)CCC1=CC=CC(=C1)C2=CC=CC=C2
InChI	1S/C16H19N/c1-17(2)12-11-14-7-6-10-16(13-14)15-8-4-3-5-9-15/h3-10,13H,11-12H2,1-2H3
InChIKey	ZMTHYJFLTGNPHJ-UHFFFAOYSA-N
PubChem Compound ID	44431718
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Inhibitor	[528780]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 528780	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3018-22. Epub 2007 Mar 23.Novel aminoethylbiphenyls as 5-HT7 receptor ligands.
Ref 528780	Bioorg Med Chem Lett. 2007 Jun 1;17(11):3018-22. Epub 2007 Mar 23.Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

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