Drug Information

Drug General Information
Drug ID
D0B5MU
Former ID
DNC011229
Drug Name
SB-207710
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539661]
Structure
Download
2D MOL

3D MOL
Formula
C19H27IN2O4
InChI
InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3
InChIKey
FCKKCDRMGKXQDK-UHFFFAOYSA-N
PubChem Compound ID
5311423
PubChem Substance ID
7980566, 11056494, 14809756, 39341099, 53219391, 57359474, 85216152, 103341399, 114156055, 123106973, 127826302, 134348434, 135650986, 139521394, 179293978, 229002534
Target and Pathway
Target(s) 5-hydroxytryptamine 4 receptor Target Info Inhibitor [531144]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT4 type receptor mediated signaling pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 539661(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 257).
Ref 531144J Med Chem. 2010 Oct 14;53(19):7035-47.Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomography.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.