Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0BP9C
|
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| Former ID |
DAP001476
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| Drug Name |
Etravirine
|
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| Synonyms |
Intelence; DAPY deriv; Diaminopyrimidine deriv; R 165335; R165335; TMC 125; TMC125; Intelence (TN); Intelence(TM); R-165335; R165335-TMC125; TMC-125; Etravirine (JAN/USAN/INN); TMC-125/R-165335; 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-benzonitrile; 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE; 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile; 65B; ETR
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| Drug Type |
Small molecular drug
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| Structure |
|
Download2D MOL |
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| Formula |
C20H15BrN6O
|
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| Canonical SMILES |
CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#<br />N
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| InChI |
1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)
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| InChIKey |
PYGWGZALEOIKDF-UHFFFAOYSA-N
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| CAS Number |
CAS 269055-15-4
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| PubChem Compound ID | |||||
| PubChem Substance ID |
642445, 832707, 7885445, 10261828, 12015430, 14856802, 33514683, 47206062, 50755335, 57397726, 58108352, 92765305, 92765307, 93375510, 93619697, 99443662, 103268452, 103999716, 113457302, 118844113, 125346599, 126617154, 126632876, 126665857, 131308179, 134224563, 134338670, 135171617, 135611140, 135693135, 136946574, 136980023, 137006543, 139263775, 143497676, 144115317, 152035774, 152234808, 152258935, 160647779, 160658773, 160968275, 162009794, 162011438, 162200353, 162849709, 163894003, 164831834, 170483270, 170503235
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| SuperDrug ATC ID |
J05AG04
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| Drug Resistance Mutation (DRM) | |||||
| DRM | DRM Info | ||||
| Target and Pathway | |||||
| Target(s) | HIV reverse transcriptase | Target Info | Modulator | [529941] | |
| References | |||||
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