Drug General Information
Drug ID
D0BW3P
Former ID
DCL000033
Drug Name
Aerovant
Indication Asthma [ICD10:J45] Phase 2a [536958]
Company
Aerovance
Target and Pathway
Target(s) Interleukin-4 receptor alpha chain Target Info Antagonist [551430]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Inflammatory bowel disease (IBD)
NetPath Pathway IL2 Signaling Pathway
IL4 Signaling Pathway
EGFR1 Signaling Pathway
PANTHER Pathway Interleukin signaling pathway
Pathway Interaction Database p73 transcription factor network
IL4-mediated signaling events
WikiPathways Inflammatory Response Pathway
IL-4 Signaling Pathway
References
Ref 536958Emerging drugs for asthma. Expert Opin Emerg Drugs. 2008 Dec;13(4):643-53.
Ref 551430Aerovance starts trial of Aerovant for uncontrolled asthma. Aerovance. March 3, 2009.

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