Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0BW9V
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| Former ID |
DIB018162
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| Drug Name |
[125I]LSD
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| Synonyms |
[125I]N,N-diethyllysergamide; [125I]lysergamid; [125I]lysergic acid diethylamide; [125I]lysergide
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [539686] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C20H24IN3O
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| InChI |
InChI=1S/C20H24IN3O/c1-4-24(5-2)20(25)12-9-14-13-7-6-8-16-18(13)15(19(21)22-16)10-17(14)23(3)11-12/h6-9,12,17,22H,4-5,10-11H2,1-3H3/t12-,17-/m1/s1/i21-2
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| InChIKey |
OBCUQRYIGTWROI-YUPRZBKSSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 7 receptor | Target Info | Agonist | [534026] | |
| 5-ht5b receptor | Target Info | Agonist | [534041] | ||
| 5-hydroxytryptamine 1F receptor | Target Info | Agonist | [526750] | ||
| 5-hydroxytryptamine 5A receptor | Target Info | Agonist | [526046] | ||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| 5HT1 type receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| PathWhiz Pathway | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | ||||
| References | |||||
| Ref 526046 | Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution. Eur J Pharmacol. 2001 Apr 27;418(3):157-67. | ||||
| Ref 526750 | Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus. J Biol Chem. 1992 Oct 5;267(28):19761-4. | ||||
| Ref 534026 | A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms. Neuron. 1993 Sep;11(3):449-58. | ||||
| Ref 534041 | Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol. 1993 Mar;43(3):313-9. | ||||
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