Drug Information

Drug General Information
Drug ID
D0BZ3S
Former ID
DNC012229
Drug Name
Phenyl-(9-phenyl-9H-purin-6-yl)-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529774]
Structure
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2D MOL

3D MOL
Formula
C17H13N5
Canonical SMILES
C1=CC=C(C=C1)NC2=NC=NC3=C2N=CN3C4=CC=CC=C4
InChI
1S/C17H13N5/c1-3-7-13(8-4-1)21-16-15-17(19-11-18-16)22(12-20-15)14-9-5-2-6-10-14/h1-12H,(H,18,19,21)
InChIKey
UKZXHZUTIYUUII-UHFFFAOYSA-N
PubChem Compound ID
12483819
Target and Pathway
Target(s) Adenosine A1 receptor Target Info Inhibitor [529774]
KEGG Pathway cGMP-PKG signaling pathway
cAMP signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interaction
Morphine addiction
NetPath Pathway TCR Signaling Pathway
RANKL Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.
Ref 529774J Med Chem. 1991 Sep;34(9):2877-82.N6,9-disubstituted adenines: potent, selective antagonists at the A1 adenosine receptor.

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