Drug General Information
Drug ID	D0C2CY
Former ID	DNC006926
Drug Name	WAY-254011
Indication	Discovery agent		Investigative	[530094]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Oxysterols receptor LXR-beta	Target Info	Inhibitor	[530094]
	Oxysterols receptor LXR-alpha	Target Info	Inhibitor	[530094]
KEGG Pathway	PPAR signaling pathway
	Non-alcoholic fatty liver disease (NAFLD)
	Hepatitis C
Pathway Interaction Database	RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SREBP signalling
	Nuclear ReceptorsWP299:Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	PPAR Alpha Pathway
	Liver X Receptor Pathway
	Adipogenesis
	SREBF and miR33 in cholesterol and lipid homeostasis
	Nuclear Receptors
References
Ref 530094	Bioorg Med Chem. 2009 May 15;17(10):3519-27. Epub 2009 Apr 12.Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRbeta.
Ref 530094	Bioorg Med Chem. 2009 May 15;17(10):3519-27. Epub 2009 Apr 12.Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRbeta.

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