Drug Information

Drug General Information
Drug ID
D0C9ZN
Former ID
DNC014302
Drug Name
3,5-bis(2-methylpyridin-4-yl)-1H-1,2,4-triazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530410]
Structure
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2D MOL

3D MOL
Formula
C14H13N5
Canonical SMILES
CC1=NC=CC(=C1)C2=NC(=NN2)C3=CC(=NC=C3)C
InChI
1S/C14H13N5/c1-9-7-11(3-5-15-9)13-17-14(19-18-13)12-4-6-16-10(2)8-12/h3-8H,1-2H3,(H,17,18,19)
InChIKey
VTUBKJFCLVZEFR-UHFFFAOYSA-N
PubChem Compound ID
20309751
Target and Pathway
Target(s) Xanthine dehydrogenase/oxidase Target Info Inhibitor [530410]
BioCyc Pathway Purine nucleotides degradation
Urate biosynthesis/inosine 5'-phosphate degradation
Guanosine nucleotides degradation
Adenosine nucleotides degradation
Retinoate biosynthesis II
KEGG Pathway Purine metabolism
Caffeine metabolism
Drug metabolism - other enzymes
Metabolic pathways
Peroxisome
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Purine metabolism
PathWhiz Pathway Caffeine Metabolism
Purine Metabolism
Reactome Purine catabolism
WikiPathways Oxidative Stress
Effects of Nitric Oxide
Metabolism of nucleotides
Selenium Micronutrient Network
References
Ref 530410Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9. Epub 2009 Sep 2.Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [corrected].
Ref 530410Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9. Epub 2009 Sep 2.Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [corrected].

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