Drug General Information
Drug ID
D0D1XW
Former ID
DIB010936
Drug Name
PEG-Interferon lambda (IL-29)
Indication Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2] Phase 1 [522171]
Company
ZymoGenetics
Target and Pathway
Target(s) Interleukin-29 ligand Target Info Agonist [531043]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
WikiPathways Type III interferon signaling
References
Ref 522171ClinicalTrials.gov (NCT00565539) Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection. U.S. National Institutes of Health.
Ref 531043Preclinical and clinical development of pegylated interferon-lambda 1 in chronic hepatitis C. J Interferon Cytokine Res. 2010 Aug;30(8):591-5.

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