Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0D5SK
|
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| Former ID |
DIB019831
|
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| Drug Name |
ethyketazocine
|
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| Synonyms |
(+/-)-EKC; WIN-35,197-2
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [538987] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H25NO2
|
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| InChI |
InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17-,19-/m1/s1
|
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| InChIKey |
SEJUQQOPVAUETF-QHLBDZCJSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Delta-type opioid receptor | Target Info | Agonist | [534018] | |
| Kappa-type opioid receptor | Target Info | Agonist | [534443] | ||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathway | |||||
| References | |||||
| Ref 534018 | Cloning and functional comparison of kappa and delta opioid receptors from mouse brain. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6736-40. | ||||
| Ref 534443 | Activation of the cloned human kappa opioid receptor by agonists enhances [35S]GTPgammaS binding to membranes: determination of potencies and efficacies of ligands. J Pharmacol Exp Ther. 1997 Aug;282(2):676-84. | ||||
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