Drug General Information
Drug ID
D0D7GG
Former ID
DNC009353
Drug Name
1-(1-Benzyl-2-biphenyl-4-yl-ethyl)-1H-imidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529684]
Structure
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2D MOL

3D MOL

Formula
C24H22N2
Canonical SMILES
C1=CC=C(C=C1)CC(CC2=CC=C(C=C2)C3=CC=CC=C3)N4C=CN=C4
InChI
1S/C24H22N2/c1-3-7-20(8-4-1)17-24(26-16-15-25-19-26)18-21-11-13-23(14-12-21)22-9-5-2-6-10-22/h1-16,19,24H,17-18H2
InChIKey
BHZGAVDQPKAVLD-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Cytochrome P450 19 Target Info Inhibitor [529684]
BioCyc Pathway Superpathway of steroid hormone biosynthesis
Estradiol biosynthesis II
Estradiol biosynthesis I
KEGG Pathway Steroid hormone biosynthesis
Metabolic pathways
Ovarian steroidogenesis
NetPath Pathway FSH Signaling Pathway
PANTHER Pathway Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway Androgen and Estrogen Metabolism
Reactome Endogenous sterols
WikiPathways Metapathway biotransformation
Tryptophan metabolism
Oxidation by Cytochrome P450
Ovarian Infertility Genes
Metabolism of steroid hormones and vitamin D
FSH signaling pathway
Integrated Breast Cancer Pathway
Phase 1 - Functionalization of compounds
References
Ref 529684Bioorg Med Chem. 2008 Sep 15;16(18):8349-58. Epub 2008 Aug 26.CYP19 (aromatase): exploring the scaffold flexibility for novel selective inhibitors.
Ref 529684Bioorg Med Chem. 2008 Sep 15;16(18):8349-58. Epub 2008 Aug 26.CYP19 (aromatase): exploring the scaffold flexibility for novel selective inhibitors.

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