TTD | Drug: D0D7YA

Drug General Information
Drug ID	D0D7YA
Former ID	DIB015595
Drug Name	DSP-6952
Synonyms	Serotonin 4 receptor partial agonist (constipation), Dainippon Sumitomo
Indication	Constipation [ICD9: 564; ICD10:K59.0]		Phase 2	[549293]
Company	Dainippon Sumitomo Pharma Co Ltd
Target and Pathway
Target(s)	5-hydroxytryptamine 4 receptor	Target Info	Agonist	[550349]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT4 type receptor mediated signaling pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome	Serotonin receptors
Reactome	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 549293	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034751)
Ref 550349	DSP-6952, a high affinity serotonin (5-HT4) receptor partial agonist. Sumitomo Dainippon Pharma Co. Ltd.

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Drug Information