Drug General Information
Drug ID	D0DX6L
Former ID	DIB010918
Drug Name	SDZ-PSD-958
Indication	Psychiatric disorder [ICD9: 290-319; ICD10:F01-F99]		Terminated	[546576]
Company	Sandoz Pharma Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	N1([C@H]2[C@H](N(CC1)C)Cc1c(C2)c(O)ccc1)c1c(cc(cc1)Cl)C
CAS Number	CAS 149811-12-1
Target and Pathway
Target(s)	Dopamine D1 receptor	Target Info	Modulator	[534179]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Morphine addiction
	Alcoholism
PANTHER Pathway	Dopamine receptor mediated signaling pathway
PathWhiz Pathway	Dopamine Activation of Neurological Reward System
Reactome	Dopamine receptors
	G alpha (s) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546576	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009027)
Ref 534179	SDZ PSD 958, a novel D1 receptor antagonist with potential limbic selectivity. J Neural Transm. 1996;103(3):261-76.

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