Drug General Information
Drug ID
D0E1NK
Former ID
DNC011711
Drug Name
N-Hydroxy-N-methyl-3-phenanthren-3-yl-acrylamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532087]
Structure
Download
2D MOL

3D MOL

Formula
C18H15NO2
Canonical SMILES
CN(C(=O)C=CC1=CC2=C(C=CC3=CC=CC=C32)C=C1)O
InChI
1S/C18H15NO2/c1-19(21)18(20)11-7-13-6-8-15-10-9-14-4-2-3-5-16(14)17(15)12-13/h2-12,21H,1H3/b11-7+
InChIKey
IPSMBZZRHPTXDJ-YRNVUSSQSA-N
PubChem Compound ID
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [532087]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.
Ref 532087J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.