Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0E5DP
|
||||
| Former ID |
DNCL002705
|
||||
| Drug Name |
Cixutumumab
|
||||
| Synonyms |
LY3012217
|
||||
| Drug Type |
Monoclonal antibody
|
||||
| Indication | Liver cancer; Non-small cell lung cancer [ICD9: 140-229, 155, 203.0; ICD10:C22, C33-C34] | Phase 2 | [523234] | ||
| Company |
Lilly
|
||||
| CAS Number |
CAS 947687-12-9
|
||||
| Target and Pathway | |||||
| Target(s) | Insulin-like growth factor I receptor | Target Info | Modulator | [533208] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| FoxO signaling pathway | |||||
| Oocyte meiosis | |||||
| Endocytosis | |||||
| PI3K-Akt signaling pathway | |||||
| AMPK signaling pathway | |||||
| Focal adhesion | |||||
| Adherens junction | |||||
| Signaling pathways regulating pluripotency of stem cells | |||||
| Long-term depression | |||||
| Ovarian steroidogenesis | |||||
| Progesterone-mediated oocyte maturation | |||||
| Pathways in cancer | |||||
| Transcriptional misregulation in cancer | |||||
| Proteoglycans in cancer | |||||
| Glioma | |||||
| Prostate cancer | |||||
| Melanoma | |||||
| References | |||||
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