Drug Information

Drug General Information
Drug ID
D0E7PZ
Former ID
DIB008919
Drug Name
NOX-B11
Synonyms
L-NOX-B11; Spiegelmers (ghrelin antagonist, obesity), NOXXON/Pfizer
Indication Obesity [ICD9: 278; ICD10:E66] Investigative [543633]
Company
NOXXON Pharma AG
Target and Pathway
Target(s) Growth hormone secretagogue receptor type 1 Target Info Antagonist [543633]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway Leptin Signaling Pathway
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543633(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).
Ref 543633(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 246).

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