Drug General Information
Drug ID	D0EE8V
Former ID	DNCL003484
Drug Name	JNJ-42756493
Indication	Lymphoma [ICD9: 202.8, 208.9; ICD10:C81-C86]		Phase 1/2	[549426]
Company	Janssen Research & Development
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Basic fibroblast growth factor receptor 1	Target Info	Modulator	[543495]
KEGG Pathway	MAPK signaling pathway
	Ras signaling pathway
	Rap1 signaling pathway
	PI3K-Akt signaling pathway
	Adherens junction
	Signaling pathways regulating pluripotency of stem cells
	Regulation of actin cytoskeleton
	Pathways in cancer
	Proteoglycans in cancer
	Prostate cancer
	Melanoma
	Central carbon metabolism in cancer
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	Angiogenesis
	FGF signaling pathway
Pathway Interaction Database	Glypican 1 network
	Syndecan-4-mediated signaling events
	N-cadherin signaling events
	FGF signaling pathway
WikiPathways	Regulation of Actin Cytoskeleton
	Endochondral Ossification
	MAPK Signaling Pathway
	Mesodermal Commitment Pathway
	Hair Follicle Development: Induction (Part 1 of 3)
	Integrated Pancreatic Cancer Pathway
	Signaling Pathways in Glioblastoma
	Neural Crest Differentiation
	Signaling by FGFR
References
Ref 549426	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800036975)
Ref 543495	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1808).

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