Drug Information

Drug General Information
Drug ID
D0EO5P
Former ID
DNC006821
Drug Name
1-(2-(2-ethylphenyl)-1-phenylethyl)piperazine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528224]
Structure
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2D MOL

3D MOL
Formula
C20H26N2
Canonical SMILES
CCC1=CC=CC=C1CC(C2=CC=CC=C2)N3CCNCC3
InChI
1S/C20H26N2/c1-2-17-8-6-7-11-19(17)16-20(18-9-4-3-5-10-18)22-14-12-21-13-15-22/h3-11,20-21H,2,12-16H2,1H3
InChIKey
USQDYFAONFKQLW-UHFFFAOYSA-N
PubChem Compound ID
44414709
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [528224]
Sodium-dependent serotonin transporter Target Info Inhibitor [528224]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 528224Bioorg Med Chem Lett. 2006 Aug 15;16(16):4345-8. Epub 2006 Jun 5.N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.
Ref 528224Bioorg Med Chem Lett. 2006 Aug 15;16(16):4345-8. Epub 2006 Jun 5.N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.

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