Drug General Information
Drug ID	D0EP5O
Former ID	DIB013874
Drug Name	NS-377
Indication	Alzheimer disease [ICD9: 331; ICD10:G30]		Terminated	[545922]
Company	NeuroSearch A/S
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c12c(C(=O)C(=O)N2)cc(c2c1CN(C2)CC)c1ccccc1
CAS Number	CAS 160753-45-7
Target and Pathway
Target(s)	Glutamate receptor AMPA subtype	Target Info	Antagonist	[534702]
References
Ref 545922	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005356)
Ref 534702	In vivo and in vitro evaluation of AMPA receptor antagonists in rat hippocampal neurones and cultured mouse cortical neurones. Eur J Pharmacol. 1998 Jul 24;353(2-3):159-67.

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