TTD | Drug: D0EY0A

Drug General Information
Drug ID	D0EY0A
Former ID	DCL001155
Drug Name	AZD7687
Drug Type	Small molecular drug
Indication	Obesity; Diabetes [ICD9: 250, 278; ICD10:E08-E13, E66]		Phase 1	[542772], [550290]
Company	AstraZeneca
Structure		Download 2D MOL
Formula	C21H25N3O3
InChI	InChI=1S/C21H25N3O3/c1-12-19(24-20(21(22)27)13(2)23-12)17-9-7-16(8-10-17)15-5-3-14(4-6-15)11-18(25)26/h7-10,14-15H,3-6,11H2,1-2H3,(H2,22,27)(H,25,26)/t14-,15-
InChIKey	YXFNPRHZMOGREC-SHTZXODSSA-N
PubChem Compound ID	42636350
Target and Pathway
Target(s)	Diglyceride acyltransferase	Target Info	Inhibitor	[550290]
BioCyc Pathway	Triacylglycerol biosynthesis
KEGG Pathway	Glycerolipid metabolism
	Retinol metabolism
	Metabolic pathways
	Fat digestion and absorption
PathWhiz Pathway	Retinol Metabolism
Reactome	Acyl chain remodeling of DAG and TAG
Reactome	Triglyceride Biosynthesis
WikiPathways	Vitamin A and Carotenoid Metabolism
	Statin Pathway
	Triacylglyceride Synthesis
	Glycerophospholipid biosynthesis
	Fatty acid, triacylglycerol, and ketone body metabolism
References
Ref 542772	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7827).
Ref 550290	Clinical pipeline report, company report or official report of AstraZeneca (2011).
Ref 550290	Clinical pipeline report, company report or official report of AstraZeneca (2011).

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Drug Information