Drug General Information
Drug ID
D0F9SG
Former ID
DAP001224
Drug Name
Dexfenfluramine
Synonyms
Acino; Adifax; Adipomin; DEXFENFLURAN; Dexafenfluramine; Dexfenfluramina; Dexfenfluraminum; Dextrofenfluramine; Fenfluramina; Fenfluramine; Fenfluraminum; Isomeride; Obedrex; Pesos; Ponderex; Rotondin; Dexfenfluramina [Spanish]; Dexfenfluraminum [Latin]; Fenfluramina [DCIT]; Fenfluramine hydrochloride; Levofenfluramine [INN]; Ponderax PA; S 768; D-Fenfluramine; Dexfenfluramine (INN); Dexfenfluramine [INN:BAN]; Fenfluramine (INN); Fenfluramine [INN:BAN]; Fenfluraminum [INN-Latin]; Ponderax (TN); Redux (TN); Fenfluramine, (+-)-Isomer; N-Ethyl-alpha-methyl-3-trifluoromethylphenethylamine; D-N-Ethyl-alpha-methyl-m-trifluoromethylphenethylamine; N-Ethyl-alpha-methyl-3-(trifluoromethyl)benzeneethanamine;N-Ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine; N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine; Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-(9CI); Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-, (S)-(9CI); Benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-, (+-)-(9CI); (+)-Fenfluramine; (+-)-Fenfluramine; (+/-)-Fenfluramine hydrochloride; (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine; (S)-Fenfluramine; (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine; 1-(m-trifluoromethyl-phenyl)-2-ethylaminopropane; 1-(meta-Trifluoromethyl-phenyl)-2 ethylaminopropane; 2-Ethylamino-1-(3-trifluoromethylphenyl)propane; 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Withdrawn from market [537068]
Therapeutic Class
Appetite Depressants
Company
Wyeth Pharmaceuticals
Structure
Download
2D MOL

3D MOL

Formula
C12H16F3N
Canonical SMILES
CCNC(C)CC1=CC(=CC=C1)C(F)(F)F
InChI
1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
InChIKey
DBGIVFWFUFKIQN-VIFPVBQESA-N
CAS Number
CAS 3239-44-9
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
A08AA04
SuperDrug CAS ID
cas=003239449
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info Inhibitor [536335]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 537068Obesity: pathophysiology and clinical management. Curr Med Chem. 2009;16(4):506-21.
Ref 536335Serotonergic drugs : effects on appetite expression and use for the treatment of obesity. Drugs. 2007;67(1):27-55.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.