Drug General Information
Drug ID	D0GY0O
Former ID	DIB002345
Drug Name	BAY-X-7195
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Phase 2	[545585]
Company	Bayer AG
Structure		Download 2D MOL 3D MOL
Formula	C30H32O6S
Canonical SMILES	C(=O)(c1ccc(S[C@H](/C=C\Cc2ccc(cc2)OCCCCOc2ccccc2)CCC(=<br />O)O)cc1)O
CAS Number	CAS 143538-27-6
PubChem Compound ID	6442328
Target and Pathway
Target(s)	Cysteinyl leukotriene receptor 1	Target Info	Modulator
	Leukotriene CysLT2 receptor	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interactionhsa04020:Calcium signaling pathway
	Neuroactive ligand-receptor interaction
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
	IL4 Signaling Pathway
	IL3 Signaling PathwayNetPath_16:IL4 Signaling Pathway
	IL3 Signaling Pathway
Pathway Interaction Database	Endothelinsendothelinpathway:Endothelins
Reactome	Leukotriene receptors
	G alpha (q) signalling eventsR-HSA-391906:Leukotriene receptors
	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
	GPCR downstream signaling
References
Ref 545585	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003794)

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