Drug General Information
Drug ID	D0H0IA
Former ID	DIB005487
Drug Name	WY-28342
Indication	Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06]		Terminated	[545972]
Company	Wyeth-Ayerst International Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	n1c(c(cc2c1CCCCC2)C)C(c1ccc(cc1)C)O
CAS Number	CAS 127890-54-4
Target and Pathway
Target(s)	Cyclooxygenase	Target Info	Modulator	[533715]
	Arachidonate 5-lipoxygenase	Target Info	Modulator	[533715]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 545972	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005582)
Ref 533715	Synthesis and antiinflammatory activity of certain 5,6,7,8-tetrahydroquinolines and related compounds. J Med Chem. 1995 Apr 28;38(9):1473-81.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.