Drug General Information
Drug ID
D0H4CB
Former ID
DIB015293
Drug Name
Hemoglobin raffimer
Synonyms
Hemolink; Cross-linked hemoglobin, Hemosol
Indication Anemia [ICD9: 280-285; ICD10:D50-D64] Phase 2/3 [521517]
Company
Ontario Inc
CAS Number
CAS 197462-97-8
Target and Pathway
Target(s) Hemoglobin Target Info Modulator [527505]
KEGG Pathway African trypanosomiasis
Malaria
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Scavenging of heme from plasma
WikiPathways Binding and Uptake of Ligands by Scavenger Receptors
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
Factors involved in megakaryocyte development and platelet production
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 521517ClinicalTrials.gov (NCT00038454) Phase II Study To Evaluate The Safety and Efficacy of Hemoglobin Raffimer in Patients Undergoing First Time CABG Surgery. U.S. National Institutes of Health.
Ref 527505Use of hemoglobin raffimer for postoperative life-threatening anemia in a Jehovah's Witness. Can J Anaesth. 2005 Apr;52(4):369-73.

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