Drug Information

Drug General Information
Drug ID
D0H4GN
Former ID
DAP000693
Drug Name
Desflurane
Synonyms
Desflurano; Desfluranum; Suprane; I 653; I653; PC6781E; Desflurane [USAN:INN]; Desflurano [INN-Spanish]; Desfluranum [INN-Latin]; I-653; R-e 236ea1; Suprane (TN); Desflurane (JAN/USP/INN); Difluoromethyl 1,2,2,2-tetrafluoroethyl ether; (+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether; 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane; 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane
Drug Type
Small molecular drug
Indication Anesthesia [ICD9: 338; ICD10:R20.0] Approved [538538], [542164]
Therapeutic Class
Anesthetics
Structure
Download
2D MOL

3D MOL
Formula
C3H2F6O
InChI
InChI=1S/C3H2F6O/c4-1(3(7,8)9)10-2(5)6/h1-2H
InChIKey
DPYMFVXJLLWWEU-UHFFFAOYSA-N
CAS Number
CAS 57041-67-5
PubChem Compound ID
42113
PubChem Substance ID
9722, 3160485, 4908648, 7847612, 7979042, 8177466, 11533490, 12014271, 15219463, 34707669, 46505270, 49966554, 57312650, 76342437, 95695185, 103770716, 104338752, 117502900, 125372049, 127770141, 131499044, 132511024, 134222145, 134337982, 135004119, 135590730, 137008121, 139078453, 143456975, 160964523, 162874517, 163693523, 164808504, 172873428, 178103731, 179150679, 184555027, 206257182, 224228880, 226444351, 249913775, 251888228, 252365870, 252492104
ChEBI ID
ChEBI:4445
SuperDrug ATC ID
N01AB07
SuperDrug CAS ID
cas=057041675
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Antagonist [535164]
References
Ref 538538FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 020118.
Ref 542164(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7156).
Ref 535164Modulation of NMDA receptor function by ketamine and magnesium. Part II: interactions with volatile anesthetics. Anesth Analg. 2001 May;92(5):1182-91.

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