Drug General Information
Drug ID	D0I6II
Former ID	DNC008149
Drug Name	3,4-dihydroquinazolin-2-amine hydrobromide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529148]
Structure		Download 2D MOL 3D MOL
Formula	C8H10BrN3
Canonical SMILES	C1C2=CC=CC=C2NC(=N1)N.Br
InChI	1S/C8H9N3.BrH/c9-8-10-5-6-3-1-2-4-7(6)11-8;/h1-4H,5H2,(H3,9,10,11);1H
InChIKey	RXCXYMVUYRKQAO-UHFFFAOYSA-N
PubChem Compound ID	45263885
Target and Pathway
Target(s)	5-hydroxytryptamine 5A receptor	Target Info	Inhibitor	[529148]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome	Serotonin receptors
	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529148	Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.
Ref 529148	Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.

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