TTD | Drug: D0I8GD

Drug General Information
Drug ID	D0I8GD
Former ID	DIB020419
Drug Name	MRS1186
Synonyms	MRS-1186
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[467929]
Structure		Download 2D MOL
Formula	C16H12ClN5O2
InChI	InChI=1S/C16H12ClN5O2/c1-2-13(23)19-16-18-11-6-5-9(17)8-10(11)15-20-14(21-22(15)16)12-4-3-7-24-12/h3-8H,2H2,1H3,(H,18,19,23)
InChIKey	SPZIDRYLSXDAEF-UHFFFAOYSA-N
PubChem Compound ID	10065929
PubChem Substance ID	15050973, 22483418, 44182946, 75624221, 103310469, 103950590, 129272011, 135650646, 227851335
Target and Pathway
Target(s)	Adenosine A3 receptor	Target Info	Antagonist	[534241]
Reactome	Adenosine P1 receptors
Reactome	G alpha (i) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCRs, Other
References
Ref 467929	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 469).
Ref 534241	Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype. J Med Chem. 1996 Oct 11;39(21):4142-8.

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Drug Information