Drug General Information
Drug ID	D0I8RY
Former ID	DIB000713
Drug Name	SDZ-ICM-567
Synonyms	5-HT3 antagonist, Novartis
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Terminated	[534522]
Company	Novartis AG
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1ccc2c(c1OC)[nH]cc2C(=O)O[C@H]1C[C@@H]2N([C@@H](CC2)C1<br />)C.Cl
Target and Pathway
Target(s)	5-Hydroxytryptamine 3 receptor	Target Info	Antagonist	[533740]
References
Ref 534522	Determination of SDZ ICM 567 in blood and muscle microdialysis samples by microbore liquid chromatography with ultraviolet and fluorescence detection. J Chromatogr B Biomed Sci Appl. 1997 Oct 24;700(1-2):191-200.
Ref 533740	Microdialysis sampling to determine the pharmacokinetics of unbound SDZ ICM 567 in blood and brain in awake, freely-moving rats. Pharm Res. 1995 Feb;12(2):291-4.

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