Drug General Information
Drug ID
D0I9UH
Former ID
DIB008396
Drug Name
MOXIFETIN HYDROGEN MALEATE
Synonyms
VUFB-15468; 2-(3-Hydroxyphenylsulfanyl)-N,N-dimethylbenzylamine hydrogen maleate; 3-[2-(Dimethylaminomethyl)phenylsulfanyl]phenol hydrogen maleate
Drug Type
Antibody
Indication Mood disorder [ICD10:F30-F39] Terminated [544967]
Structure
Download
2D MOL

3D MOL

Formula
C19H21NO5S
Canonical SMILES
CN(C)CC1=CC=CC=C1SC2=CC=C(C=C2)O.C(=CC(=O)O)C(=O)O
InChI
1S/C15H17NOS.C4H4O4/c1-16(2)11-12-5-3-4-6-15(12)18-14-9-7-13(17)8-10-14;5-3(6)1-2-4(7)8/h3-10,17H,11H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChIKey
WHUIZCRTMBKGEK-WLHGVMLRSA-N
CAS Number
CAS 127906-27-8
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Sodium-dependent serotonin transporter Target Info [525355]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway 5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
WikiPathways Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 544967Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001731)
Ref 525355Moxidectin causes adult worm mortality of human lymphatic filarial parasite Brugia malayi in rodent models. Folia Parasitol (Praha). 2014 Dec;61(6):561-70.

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