Drug Information

Drug General Information
Drug ID
D0IF0C
Former ID
DNC000819
Drug Name
Isoprenaline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540790]
Structure
Download
2D MOL

3D MOL
Formula
C11H17NO3
InChI
InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3
InChIKey
JWZZKOKVBUJMES-UHFFFAOYSA-N
CAS Number
CAS 132-17-2
PubChem Compound ID
3779
PubChem Substance ID
9268, 75322, 91788, 611308, 3133594, 5272313, 8152391, 10535368, 11336069, 11361308, 11363843, 11366405, 11368967, 11371528, 11373566, 11377129, 11462280, 11467125, 11468245, 11484778, 11486793, 11488877, 11490290, 11491839, 11494763, 11534308, 14748912, 24430805, 24715029, 26512260, 26752240, 29222898, 46507323, 47216837, 47291195, 47365254, 47440329, 47515375, 47810812, 47959817, 48334566, 48416134, 49892804, 49892806, 49892807, 50104946, 50111114, 53790889, 56313305, 56313643
ChEBI ID
ChEBI:6046
SuperDrug ATC ID
C01CA02; R03AB02; R03CB01
SuperDrug CAS ID
cas=007683592
Target and Pathway
Target(s) Beta-1 adrenergic receptor Target Info Agonist [538095]
Beta-2 adrenergic receptor Target Info Agonist [538095]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Gap junction
Salivary secretion
Dilated cardiomyopathyhsa04020:Calcium signaling pathway
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta1 adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
PathWhiz Pathway Muscle/Heart Contraction
Reactome Adrenoceptors
G alpha (s) signalling eventsR-HSA-390696:Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Endothelin Pathways
GPCR ligand binding
GPCR downstream signalingWP58:Monoamine GPCRs
Vitamin D Receptor Pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 540790(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 536).
Ref 538095Current therapeutic uses and potential of beta-adrenoceptor agonists and antagonists. Eur J Clin Pharmacol. 1998 Feb;53(6):389-404.

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