Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J1GR
|
||||
| Former ID |
DCL000359
|
||||
| Drug Name |
CP-868596
|
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| Drug Type |
Small molecular drug
|
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| Therapeutic Class |
Anticancer Agents
|
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| Company |
Pfizer
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C26H29N5O2
|
||||
| InChI |
InChI=1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,27H2,1H3
|
||||
| InChIKey |
DYNHJHQFHQTFTP-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
15379617, 22724199, 33999151, 78995356, 135267953, 135349234, 135626820, 136340262, 136349573, 136367704, 136920312, 137263558, 139541679, 144115852, 152258467, 160647302, 160681954, 162011433, 162038138, 162202696, 164838602, 172918813, 174006528, 174530261, 184828151, 198943954, 223366211, 223400256, 223705033, 223921696, 228815749, 247785884, 252110181, 252215199, 252451666
|
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| Target and Pathway | |||||
| Target(s) | Alpha platelet-derived growth factor receptor | Target Info | Modulator | ||
| KEGG Pathway | MAPK signaling pathway | ||||
| Ras signaling pathway | |||||
| Rap1 signaling pathway | |||||
| Calcium signaling pathway | |||||
| Cytokine-cytokine receptor interaction | |||||
| Endocytosis | |||||
| PI3K-Akt signaling pathway | |||||
| Focal adhesion | |||||
| Gap junction | |||||
| Regulation of actin cytoskeleton | |||||
| HTLV-I infection | |||||
| Pathways in cancer | |||||
| MicroRNAs in cancer | |||||
| Glioma | |||||
| Prostate cancer | |||||
| Melanoma | |||||
| Central carbon metabolism in cancer | |||||
| Choline metabolism in cancer | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| PDGF signaling pathway | |||||
| Pathway Interaction Database | ATF-2 transcription factor network | ||||
| PDGFR-alpha signaling pathway | |||||
| PDGF receptor signaling network | |||||
| WikiPathways | Regulation of Actin Cytoskeleton | ||||
| Osteoblast Signaling | |||||
| Focal Adhesion | |||||
| Hair Follicle Development: Organogenesis (Part 2 of 3) | |||||
| PIP3 activates AKT signaling | |||||
| Cardiac Progenitor Differentiation | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Allograft Rejection | |||||
| Signaling Pathways in Glioblastoma | |||||
| Signaling by PDGF | |||||
| Angiogenesis | |||||
| References | |||||
| Ref 542807 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7882). | ||||
| Ref 547352 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015430) | ||||
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