Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J2TN
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| Former ID |
DAP001136
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| Drug Name |
Diphenoxylate
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| Synonyms |
Difenossilato; Difenoxilato; Diphenoxalate; Diphenoxylatum; Difenossilato [DCIT]; Difenoxilato [Spanish]; Diphenoxylate HCl; Diphenoxylate Monohydrochloride; Diphenoxylate hydrochloride; Diphenoxylatum [Latin]; NIH 7562; R 1132; Difenoxilato [INN-Spanish]; Diphenoxylate (INN); Diphenoxylate [INN:BAN]; Diphenoxylate hydrochloride (USP); Diphenoxylate hydrochloride(usp); Diphenoxylatum [INN-Latin]; Lomotil (TN); R 1132 (antiperistaltic); R-1132; Co-phenotrope (TN); Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate; Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride; Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate; Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate; Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate hydrochloride; Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester; Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidin-1-ium-4-carboxylate chloride; Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride; 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic acid ethyl ester; 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester; 1-(3-Cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid ethyl ester hydrochloride; 1-(3-cyano-3,3-diphenylpropyl)-4-(ethoxycarbonyl)-4-phenylpiperidinium chloride; 2,2-Diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile; 4-Ethoxycarbonyl-alpha,alpha,4-triphenyl-1-piperidinebutyronitrile, hydrochloride; 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester; 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester (9CI); 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, monohydrochloride; 4-ethoxycarbonyl-alpha,alpha,4-triphenyl-1-piperidinebutyronitrile hydrochloride
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Analgesics
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| Company |
Janssen Pharmaceutica
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| Structure |
|
Download2D MOL |
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| Formula |
C30H32N2O2
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| InChI |
InChI=1S/C30H32N2O2/c1-2-34-28(33)29(25-12-6-3-7-13-25)18-21-32(22-19-29)23-20-30(24-31,26-14-8-4-9-15-26)27-16-10-5-11-17-27/h3-17H,2,18-23H2,1H3
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| InChIKey |
HYPPXZBJBPSRLK-UHFFFAOYSA-N
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| CAS Number |
CAS 915-30-0
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| PubChem Compound ID | |||||
| PubChem Substance ID |
10074, 7783795, 7979104, 8160155, 15355339, 29281638, 46507130, 48415911, 49986104, 50113007, 57328164, 78231737, 85209743, 96024557, 104331935, 109613128, 117513683, 123058746, 124893434, 124963550, 126690413, 128131964, 134338381, 134980071, 137007031, 140170301, 160964415, 163350696, 163421407, 175267295, 178103739, 179225191, 184612598, 198992889, 223685216, 226427508, 241164686, 250098946, 252348517
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| SuperDrug ATC ID |
A07DA01
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| SuperDrug CAS ID |
cas=000915300
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| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Agonist | [536587] | |
| NetPath Pathway | TCR Signaling Pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
| Ref 538177 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040357. | ||||
| Ref 542173 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7164). | ||||
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