Drug General Information
Drug ID
D0J3NJ
Former ID
DIB010323
Drug Name
RP-69698
Drug Type
Small molecular drug
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Terminated [545550]
Company
Rhone-Poulenc SA
Structure
Download
2D MOL

3D MOL

Formula
C23H23N5O
Canonical SMILES
n1n[nH]c(n1)C(CCCCOc1nc(cc(c1)c1ccccc1)c1ccccc1)(C)C
CAS Number
CAS 141748-00-7
PubChem Compound ID
Target and Pathway
Target(s) Leukotriene B4 receptor 1 Target Info Modulator [526761]
KEGG Pathway Neuroactive ligand-receptor interaction
NetPath Pathway IL4 Signaling Pathway
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
GPCR ligand binding
GPCR downstream signaling
References
Ref 545550Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003683)
Ref 526761omega-[(4,6-Diphenyl-2-pyridyl)oxy]alkanoic acid derivatives: a new family of potent and orally active LTB4 antagonists. J Med Chem. 1992 Nov 13;35(23):4315-24.

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