Drug Information

Drug General Information
Drug ID
D0J9CR
Former ID
DIB018847
Drug Name
AMTB
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467477]
Structure
Download
2D MOL
Formula
C23H26N2O2S
InChI
InChI=1S/C23H26N2O2S/c1-18-7-4-8-19(15-18)17-27-22-11-3-2-10-21(22)23(26)25(13-6-12-24)16-20-9-5-14-28-20/h2-5,7-11,14-15H,6,12-13,16-17,24H2,1H3
InChIKey
LCQJRANJHOEQFG-UHFFFAOYSA-N
PubChem Compound ID
16095384
PubChem Substance ID
40064147, 111327632, 123093749, 123110405, 178100954, 235380853, 245174581
Target and Pathway
Target(s) TRPM8 protein Target Info Blocker (channel blocker) [529542]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 467477(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4132).
Ref 529542AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome. Am J Physiol Renal Physiol. 2008 Sep;295(3):F803-10.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.